Prevent Prostate Cancer and Its Recurrence with Soy

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          Soy products, particularly tofu, may be the key dietary intervention for men if you want to prevent prostate cancer, or reduce your risk for the cancer recurring after treatment.

          If you already have prostate cancer, and you are undergoing radiation treatment for it, soy consumption may help you to kill cancer cells faster.

          Here is some of the research evidence for these claims:

Soy, isoflavones, and prostate cancer. Jian L. Mol Nutr Food Res. 2009 February.  “The association between dietary factors and prostate cancer has been investigated and one explanation for the low incidence of the cancer in Asia might be high consumption of fresh vegetables including soybean and its products.”

Soy food consumption and risk of prostate cancer: a meta-analysis of observational studies. Hwang YW. Et al. Nutr Cancer. 2009. “Among individual soy foods, only tofu yielded a significant value. Consumption of soybean milk, miso, or natto did not significantly reduce the risk of prostate cancer. Genistein and daidzein were associated with a lower risk of prostate cancer.”

Radiation-induced HIF-1alpha cell survival pathway is inhibited by soy isoflavones in prostate cancer cells. Singh-Gupta V. Et al. Int J Cancer. 2009 April.  “We previously showed that treatment of prostate cancer cells with soy isoflavones and radiation resulted in greater cell killing in vitro. We extended our studies to investigate the role of HIF-1alpha survival pathway and its upstream Src and STAT3 molecules in isoflavones and radiation interaction. Our novel findings suggest that the increased responsiveness to radiation mediated by soy isoflavones could be due to pleiotropic effects of isoflavones blocking cell survival pathways induced by radiation.”

Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer. Dalais FS. Et al. Urology. 2004 September. “This work provides some evidence to support epidemiologic studies claiming that male populations who consume high phytoestrogen diets have a reduced risk of prostate cancer development and progression.”

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Posted in Prostate Health on April 30 at 07:33 AM

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